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In a clinical trial, in Stage 2 T1D patients, TZIELD delayed the median onset of Stage 3 T1D by approximately 2 years, compared to placebo.
November 18, 2022
By: Kristin Brooks
Managing Editor, Contract Pharma
Provention Bio, Inc., a biopharmaceutical company dedicated to intercepting and preventing immune-mediated diseases, received FDA approval for its Biologics License Application (BLA) for TZIELD (teplizumab-mzwv), an anti-CD3-directed antibody, as the first and only immunomodulatory treatment to delay the onset of Stage 3 T1D in adult and pediatric patients 8 years and older with stage 2 T1D. Tzield binds to certain immune system cells to delay progression to stage 3 type 1 diabetes. Tzield...
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